SAMe is a derivative of amino acid that is synthesized naturally by the body.
Methylation contributes methyl to activate certain molecules.
The synthesis of polyamines : for cell growth, gene expression,neuronal regenerationetc.
Synthesis of cysteine, glutathione and other sulphate chemical reactions.
SAMe is concentrated in the liver and brain, and is a key source of methyl donor in the synthesis of hormones, nucleic acid, proteins, phospholipids and neurotransmitters such as dopamine and serotonin. SAMe plays an important role in various metabolic processes, facilitates in the exploitation of glutathione,and maintains acetylcholine levels, helping mental functioning and preventing aging and degeneration of neurons.
In young, healthy people the SAMe is distributed throughout the body. Over time though or with the onset of illnesses these levels are reduced. Intake of folicacid, TMG, B6 and B12raises SAMe levels. SAMe aides in the composition of phosphatidylcholine, which maintains the humidity in the cell membranes and is used by the brain to create the neurotransmitter acetylcholine.
SAMe facilitates enzymatic methylation processes and stimulates the liver levels of vital antioxidant glutathione, whose reduction leads to the creation of free radicals.
CAUTION: SAMe should not be taken by those diagnosed with bipolar disorder.